Scientists from the US Food and Drug Administration have stated that the Moderna Booster that is being approved does not meet all of the criteria for an additional vaccination. The booster is probably not as effective because the first two doses still built up very high levels of protection, even if the antibodies decreased slightly (more on this below).
According to the US authorities, the Moderna booster vaccination shows an increase in antibodies, but not to a significant extent, since the antibody levels are already high after the first two Moderna vaccinations.
“There was an increase, yes. But was it high enough? Who should know? There is no antibody surge requirement that would be necessary. Nor is it clear how much the increase was in the study, ”said John Moore, professor of immunology at Weill Cornell Medical College in New York.
Eric Topol, molecular physician and head of the Scripps Research Translational Institute in La Jolla, California, said via the news agency Reutersthat the effectiveness of the Moderna Booster has “many holes”.
Except for the Pfizer refresh with data from Israel, you have no “real world” data from other boosters.