With new technology only one injection will be needed to cure HIV infections (Source: Shutterstock)

Researchers have developed a new injection that could revolutionize the lives of patients with HIVthe virus that causes aids. According to a new study published in the scientific journal Nature Biotechnology, in the future it will be possible to get rid of HIV infection with a single injection.

Today, patients with the virus must undergo a cocktail of drugs to reduce their viral load to extremely low levels, so that they do not suffer from symptoms and do not run the risk of transmitting the pathogen to others.

With new technology only one injection will be needed to cure HIV infections (Source: Shutterstock)Source: shutterstock

But this volume of medicine has many side effects. In addition, it increases the price of treatment, making access difficult for the poorest populations – usually also the most affected.

That’s why researchers at Tel Aviv University have tackled the challenge of developing a revolutionary treatment for the disease. Based on a single injection, they developed a technology that might be able to cure the infection.

Adi Barzel, author of the study, explains in a note that the technique he developed is based on the use of modified type B white blood cells. The group’s first challenge was to grow these cells outside the human body.

Genetically modified cells

The researcher says that “until now, only a few scientists, and we among them, had been able to create B cells outside the body.” That done, they used the CRISPR (gene editing) technique to genetically modify this material.

This technology, which won the 2020 Nobel Prize in Chemistry for researchers Jennifer Doudna and Emmanuelle Charpentier, allows genes to be inserted, repaired or removed from within the DNA of living cells.

This is how Barzel managed to create B cells capable of secreting specific antibodies to fight HIV. By injecting the modified material into animals, the researchers proved the efficiency of the process.

Read too: Scientists discover why HIV is drug resistant

Barzel also says that there is no genetic treatment for AIDS today, so the approach proposed by his research group could be revolutionary.

Based on this, we can expect that in the coming years new, even more effective drugs will appear on the market – not only to treat HIV infection, but even for certain types of cancer caused by viruses.

ARTICLE Nature Biotechnology: doi.org/10.1038/s41587-022-01328-9

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