Blood samples from very old people
The researchers analyzed 51 blood samples from people over eighty (vaccinated twice) and determined how many antibodies and T lymphocytes (both form important defense mechanisms against pathogens) against SARS-CoV-2 they had formed. They then compared the values with a control group of people between the ages of 20 and 53.
The results of the study show that the test subjects had over 80 fewer antibodies and T lymphocytes than the younger ones. Five of the over 80-year-olds showed no or only few antibodies and T lymphocytes after the second bite. This corresponds to around ten percent of the test subjects.
These five sufferers received the booster 16 weeks after their first sting. “On the day of the booster vaccination, blood tests showed that there was no longer a measurable immune response to the coronavirus, “reports the Marburg virologist Dr. Christian Keller, a lead author of the study, according to the German “Health Portal “.
However, within two weeks of the third dose, four of the five boosted patients developed the same amount of antibodies as the younger group after their second sting. Even after a fourth vaccination, the fifth subject would not have shown “an adequate immune response,” according to Keller.
The virologist emphasizes the importance of the third stitch in very old patients: “The data have become even more relevant since the appearance of the new Omikron variant, as particularly pronounced immune responses are required for their defense. The risk group of people over 80 should definitely take advantage of an early booster vaccination.”